
The estrogen-replacement drug Premarin, prescribed to menopausal women, is made from horse urine; in fact, the drug’s name is short for PREgnant MARes’ urINe. Like Premarin, Cenestin contains a complex mixture of conjugated estrogens that are slowly released into the body.Click to see full answer. Thereof, how is horse urine collected for Premarin?Premarin is created by collecting the urine of pregnant mares. The mares are kept in small standing stalls in order to limit their movement, so not to displace the urinary bladder bags used to collect every drop of urine. Once the mares are full term and ready to deliver, they are turned out to have their foals.Secondly, is HRT still made from horse urine? One of the HRT drugs that has historically been among the most widely prescribed is made from animal waste. Both drugs contain horse urine, specifically pregnant mare’s urine (PMU). In this manner, is Premarin still manufactured? The most commonly known drug produced with equine urine is Premarin®, now manufactured by pharmaceutical giant Pfizer (Pfizer purchased Wyeth Pharmaceuticals, the original manufacturer of the drug, in 2009).Is there a substitute for Premarin?Q: Is there a “natural” replacement for Premarin? In a sense, the most “natural” replacement for lost estrogen is estrogen, which is a prescription product (like Premarin or Estrace vaginal cream, Estring, Vagifem, or the non-estrogen Osphena).
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